Cryo-EM microscopy as a tool for studying the structure of molecules 

24. 9. 17:00-20:30
On site
Commented presentation

Understanding and eventually curing an infectious disease requires an understanding about the specific contacts between host and pathogen. The key to this understanding is precise knowledge about the molecules that are the heart of this interaction. Cryogenic electron microscopy (cryo-EM) has emerged as the most powerful technique to study the structure of such molecules which are typically proteins and their complexes at near-atomic resolution. In the Zoll lab we are isolating these molecular assemblies from genetically modified micro-organisms and prepare them for imaging. This round tour will give visitors the chance to get an overview of the various stages of sample preparation undertaken in the lab, the extensive computational calculations required for image analysis, and finally the interpretation of the 3-dimensional models of the molecules of interest. The excursion will take place in English with a simultaneous translation to the Czech language.

Please, at all times abide by the rules regarding the COVID-19 pandemic. Apart from facemasks, you may be asked for a proof of a negative test result (a valid negative test or a vaccination certificate) at some places. Check the measures of the institution(s) you are planning on visiting.

Organization

 

Institute of Organic Chemistry and Biochemistry of the CAS
AddressFlemingovo náměstí 2, 166 10 Praha 6

Traffic infozastávky Dejvická, Lotyšská, NTK, Studentský dům

Specification of locationLaboratoř

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